CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Y842C

Y842C

CIViC ID: 3070 · Gene: FLT3

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
6

Evidence Level Distribution

Level D: 6

Evidence Items

Showing CIViC evidence rows where gene = FLT3 and variant = Y842C.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsResistanceAcute Myeloid LeukemiaSorafenib4
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaLestaurtinib4
DPredictiveSupportsResistanceAcute Myeloid LeukemiaFLT3/ABL/Aurora Kinase Inhibitor KW-24493
DPredictiveSupportsResistanceAcute Myeloid LeukemiaSunitinib3
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaMidostaurin3
DPredictiveSupportsResistanceAcute Myeloid LeukemiaQuizartinib3