Variant Summary
- HGVS
- —
- Variant Type(s)
- —
- Evidence Items
- 5
Evidence Level Distribution
Level B: 3Level C: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = PTEN and variant = Expression.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Sensitivity/Response | Glioblastoma | Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor | 4 |
| B | Predictive | Supports | Sensitivity/Response | Glioblastoma | Erlotinib,Gefitinib | 3 |
| B | Predictive | Supports | Sensitivity/Response | Breast Cancer | Trastuzumab | 3 |
| D | Predictive | Supports | Sensitivity/Response | Glioblastoma | Dacomitinib | 2 |
| C | Predictive | Supports | Resistance | Her2-receptor Positive Breast Cancer | Fulvestrant,Everolimus | 1 |