CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Expression

Expression

CIViC ID: 314 · Gene: NRG1

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
6

Evidence Level Distribution

Level B: 1Level D: 5

Evidence Items

Showing CIViC evidence rows where gene = NRG1 and variant = Expression.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseHead And Neck Squamous Cell CarcinomaLapatinib4
DPredictiveSupportsResistanceColorectal CancerCetuximab4
BPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaPatritumab4
DPredictiveSupportsSensitivity/ResponseOvarian CancerSeribantumab3
DPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaCisplatin,Carboplatin,Gemcitabine,Paclitaxel3
DPredictiveSupportsSensitivity/ResponseCancerAnti-ErbB3 Monoclonal Antibody AV-2033