Variant Summary
- Also known as
- GLU322LYS
- HGVS
- ENST00000215832.6:c.964G>A,NC_000002.11:g.22127164C>T,NP_002736.3:p.Glu322Lys,NM_002745.4:c.964G>A
- Variant Type(s)
- missense_variant,gain_of_function_variant
- Evidence Items
- 1
Evidence Level Distribution
Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = MAPK1 and variant = E322K.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Sensitivity/Response | Head And Neck Squamous Cell Carcinoma | Erlotinib | 4 |