CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Loss

Loss

CIViC ID: 3202 · Gene: SMARCB1

Variant Summary

HGVS
—
Variant Type(s)
loss_of_function_variant
Evidence Items
6

Evidence Level Distribution

Level B: 6

Evidence Items

Showing CIViC evidence rows where gene = SMARCB1 and variant = Loss.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BDiagnosticSupportsPositiveAtypical Teratoid Rhabdoid Tumor4
BOncogenicSupportsOncogenicityEpithelioid Sarcoma3
BDiagnosticDoes Not SupportPositiveRhabdoid Cancer2
BDiagnosticSupportsPositiveRenal Medullary Carcinoma2
BDiagnosticSupportsPositiveRenal Medullary Carcinoma2
BDiagnosticSupportsPositiveRenal Medullary Carcinoma2