CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Amplification

Amplification

CIViC ID: 330 · Gene: NOTCH1

Variant Summary

HGVS
—
Variant Type(s)
transcript_amplification
Evidence Items
2

Evidence Level Distribution

Level B: 1Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = NOTCH1 and variant = Amplification.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseColorectal CancerNOTCH1 Antibody (PF-06293622)2
BPrognosticSupportsPoor OutcomeColorectal Cancer2