Variant Summary
- Also known as
- TPR-NTRK1
- HGVS
- —
- Variant Type(s)
- transcript_fusion
- Evidence Items
- 5
Evidence Level Distribution
Level C: 5
Evidence Items
Showing CIViC evidence rows where gene = TPR::NTRK1 and variant = Fusion.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Sensitivity/Response | Colorectal Cancer | Larotrectinib | 4 |
| C | Predictive | Supports | Sensitivity/Response | Gliosarcoma | Larotrectinib | 4 |
| C | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Larotrectinib | 3 |
| C | Predictive | Supports | Sensitivity/Response | Papillary Thyroid Carcinoma | Larotrectinib | 3 |
| C | Predictive | Supports | Sensitivity/Response | High Grade Glioma | Entrectinib | 3 |