Variant Summary
- HGVS
- —
- Variant Type(s)
- transcript_amplification
- Evidence Items
- 2
Evidence Level Distribution
Level B: 2
Evidence Items
Showing CIViC evidence rows where gene = TOP1 and variant = Amplification.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Sensitivity/Response | Colorectal Cancer | Cetuximab,FOLFIRI Regimen | 4 |
| B | Predictive | Supports | Sensitivity/Response | Colorectal Cancer | Irinotecan | 1 |