CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/EXPRESSION

EXPRESSION

CIViC ID: 384 · Gene: TOP1

Variant Summary

HGVS
—
Variant Type(s)
—
Evidence Items
2

Evidence Level Distribution

Level B: 2

Evidence Items

Showing CIViC evidence rows where gene = TOP1 and variant = EXPRESSION.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseColorectal CancerIrinotecan3
BPredictiveSupportsSensitivity/ResponseOvarian CancerTopotecan,Carboplatin,Cyclophosphamide2