Variant Summary
- Also known as
- NTRK1 Fusion
- HGVS
- —
- Variant Type(s)
- transcript_fusion
- Evidence Items
- 7
Evidence Level Distribution
Level A: 3Level B: 2Level C: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = v::NTRK1 and variant = Fusion.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| A | Predictive | Supports | Sensitivity/Response | Solid Tumor | Entrectinib | 5 |
| A | Predictive | Supports | Sensitivity/Response | Solid Tumor | Larotrectinib | 4 |
| B | Predictive | Supports | Sensitivity/Response | Sarcoma | Larotrectinib | 4 |
| D | Predictive | Supports | Sensitivity/Response | Lung Adenocarcinoma | Larotrectinib,Lestaurtinib,Crizotinib | 3 |
| A | Predictive | Supports | Sensitivity/Response | Solid Tumor | Entrectinib | 3 |
| B | Diagnostic | Supports | Positive | Lipofibromatosis-like Neural Tumor | 3 | |
| C | Predictive | Supports | Sensitivity/Response | Cancer | Larotrectinib | 2 |