Variant Summary
- Also known as
- ARG132HIS,RS121913500
- HGVS
- NM_001282386.1:c.395G>A,NP_005887.2:p.Arg132His,NC_000002.11:g.209113112C>T,ENST00000415913.1:c.395G>A
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level C: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = IDH1 and variant = R132H.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Oligodendroglioma | AGI-5198 | 4 |
| C | Predictive | Does Not Support | Sensitivity/Response | Pancreatic Ductal Adenocarcinoma | Ivosidenib | 2 |