Variant Summary
- Also known as
- ARG896CYS,R866C,R881C,RS758222990
- HGVS
- NC_000017.10:g.37881616C>T,ENST00000269571.5:c.2686C>T,NM_004448.3:c.2686C>T,NP_004439.2:p.Arg896Cys
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = ERBB2 and variant = R896C.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Breast Cancer | Neratinib | 5 |