CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/D835

D835

CIViC ID: 437 · Gene: FLT3

Variant Summary

Also known as
ASP835
HGVS
NC_000013.10:g.28592642C>A
Variant Type(s)
protein_altering_variant
Evidence Items
5

Evidence Level Distribution

Level B: 2Level C: 1Level D: 2

Evidence Items

Showing CIViC evidence rows where gene = FLT3 and variant = D835.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsResistanceAcute Myeloid LeukemiaQuizartinib,Sorafenib4
BPredictiveSupportsResistanceAcute Myeloid LeukemiaSorafenib4
DPredictiveSupportsResistanceAcute Myeloid LeukemiaQuizartinib,Ponatinib3
DPredictiveSupportsResistanceAcute Myeloid LeukemiaSU56143
CPrognosticSupportsPoor OutcomeMyelodysplastic Syndrome2