Variant Summary
- HGVS
- —
- Variant Type(s)
- —
- Evidence Items
- 5
Evidence Level Distribution
Level A: 1Level C: 3Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = ERBB2 and variant = G778_P780dup.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Breast Cancer | Neratinib | 5 |
| C | Predictive | Supports | Sensitivity/Response | Lung Adenocarcinoma | Dacomitinib | 3 |
| A | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Trastuzumab Deruxtecan | 3 |
| C | Predictive | Supports | Sensitivity/Response | Lung Adenocarcinoma | Afatinib | 3 |
| C | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Dacomitinib | 3 |