Variant Summary
- Also known as
- PHE2108LEU
- HGVS
- NC_000001.10:g.11187094G>T,ENST00000361445.4:c.6324C>A
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level C: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = MTOR and variant = F2108L.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Resistance | Thyroid Gland Carcinoma | Everolimus | 5 |
| D | Predictive | Supports | Resistance | Breast Cancer | Sirolimus | 4 |