CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/e6::e20

e6::e20

CIViC ID: 503 · Gene: EML4::ALK

Variant Summary

Also known as
EML4-ALK E6-E20
HGVS
—
Variant Type(s)
transcript_fusion
Evidence Items
8

Evidence Level Distribution

Level C: 2Level D: 6

Evidence Items

Showing CIViC evidence rows where gene = EML4::ALK and variant = e6::e20.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseLung Non-small Cell Carcinoma2,4-pyrimidinediamine4
CPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaCrizotinib4
CPredictiveSupportsSensitivity/ResponseCancerCrizotinib3
DPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaCeritinib3
DPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaALK Inhibitor TAE6842
DPredictiveDoes Not SupportSensitivity/ResponseLung Non-small Cell CarcinomaALK Inhibitor TAE6842
DPredictiveDoes Not SupportSensitivity/ResponseLung Non-small Cell CarcinomaCrizotinib2
DPredictiveDoes Not SupportSensitivity/ResponseLung Non-small Cell CarcinomaAlvespimycin2