CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 505 · Gene: GNAQ

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
4

Evidence Level Distribution

Level B: 2Level D: 2

Evidence Items

Showing CIViC evidence rows where gene = GNAQ and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseUveal MelanomaMirdametinib,Sotrastaurin Acetate4
DPredictiveSupportsSensitivity/ResponseUveal MelanomaJQ12
BPredictiveSupportsSensitivity/ResponseUveal MelanomaTrametinib2
BPredictiveSupportsSensitivity/ResponseUveal MelanomaCabozantinib2