CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 506 · Gene: GNA11

Variant Summary

HGVS
—
Variant Type(s)
—
Evidence Items
4

Evidence Level Distribution

Level B: 1Level C: 1Level D: 2

Evidence Items

Showing CIViC evidence rows where gene = GNA11 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseUveal MelanomaSotrastaurin Acetate,Mirdametinib3
BPredictiveSupportsSensitivity/ResponseUveal MelanomaCabozantinib3
CPredictiveSupportsSensitivity/ResponseUveal MelanomaTrametinib2
DPredictiveSupportsSensitivity/ResponseUveal MelanomaJQ11