Variant Summary
- HGVS
- —
- Variant Type(s)
- exon_variant
- Evidence Items
- 8
Evidence Level Distribution
Level A: 1Level B: 6Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = KIT and variant = Exon 9 Mutation.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| A | Predictive | Supports | Sensitivity/Response | Gastrointestinal Stromal Tumor | Imatinib | 4 |
| B | Predictive | Supports | Sensitivity/Response | Gastrointestinal Stromal Tumor | Sunitinib | 3 |
| B | Predictive | Supports | Sensitivity/Response | Gastrointestinal Stromal Tumor | Sunitinib | 3 |
| B | Predictive | Supports | Sensitivity/Response | Gastrointestinal Stromal Tumor | Imatinib | 3 |
| C | Predictive | Supports | Reduced Sensitivity | Gastrointestinal Stromal Tumor | Regorafenib Anhydrous | 3 |
| B | Predictive | Supports | Reduced Sensitivity | Gastrointestinal Stromal Tumor | Imatinib | 2 |
| B | Predictive | Supports | Reduced Sensitivity | Gastrointestinal Stromal Tumor | Regorafenib Anhydrous | 2 |
| B | Predictive | Supports | Sensitivity/Response | Gastrointestinal Stromal Tumor | Regorafenib Anhydrous | 2 |