CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 511 · Gene: FGFR2

Variant Summary

HGVS
—
Variant Type(s)
gain_of_function_variant,transcript_variant
Evidence Items
3

Evidence Level Distribution

Level B: 1Level C: 1Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = FGFR2 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseCholangiocarcinomaInfigratinib4
DPredictiveSupportsSensitivity/ResponseEndometrial CancerPonatinib3
CPredictiveSupportsSensitivity/ResponseCholangiocarcinomaInfigratinib2