CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 519 · Gene: FLT3

Variant Summary

HGVS
—
Variant Type(s)
gain_of_function_variant,transcript_variant
Evidence Items
3

Evidence Level Distribution

Level A: 1Level B: 2

Evidence Items

Showing CIViC evidence rows where gene = FLT3 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaGilteritinib4
APredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaMidostaurin3
BPrognosticDoes Not SupportAcute Myeloid Leukemia2