Variant Summary
- Also known as
- DEL 485-490,LEU485_PRO490DEL
- HGVS
- ENST00000288602.6:c.1453_1470del,NC_000007.13:g.140477838_140477855del,NM_004333.4:c.1453_1470del,NP_004324.2:p.Leu485_Pro490del
- Variant Type(s)
- inframe_deletion
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = BRAF and variant = L485_P490del.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Cancer | Pan-RAF Inhibitor LY3009120 | 3 |