CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

T227M

CIViC ID: 540 · Gene: FLT3

Variant Summary

Also known as
RS1933437,THR227MET
HGVS
NM_004119.2:c.680C>T,NP_004110.2:p.Thr227Met,ENST00000241453.7:c.680C>T,NC_000013.10:g.28624294G>A
Variant Type(s)
missense_variant,SNP
Evidence Items
1

Evidence Level Distribution

Level B: 1

Evidence Items

Showing CIViC evidence rows where gene = FLT3 and variant = T227M.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsAdverse ResponseRenal Cell CarcinomaSunitinib3