Variant Summary
- Also known as
- CYS1483TYR
- HGVS
- NC_000001.10:g.11217230C>T,ENST00000361445.4:c.4448G>A,NM_004958.3:c.4448G>A,NP_004949.1:p.Cys1483Tyr
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = MTOR and variant = C1483Y.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | T-cell Acute Lymphoblastic Leukemia | Sirolimus | 2 |