CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/TKD MUTATION

TKD MUTATION

CIViC ID: 56 · Gene: FLT3

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
6

Evidence Level Distribution

Level B: 6

Evidence Items

Showing CIViC evidence rows where gene = FLT3 and variant = TKD MUTATION.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsResistanceAcute Myeloid LeukemiaSorafenib4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4
BPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaMidostaurin3
BPrognosticSupportsBetter OutcomeAcute Myeloid Leukemia3
BDiagnosticDoes Not SupportPositiveAcute Myeloid Leukemia3
BPrognosticDoes Not SupportAcute Myeloid Leukemia3