Variant Summary
- Also known as
- FIP1L1-PDGFRA
- HGVS
- —
- Variant Type(s)
- transcript_fusion
- Evidence Items
- 5
Evidence Level Distribution
Level A: 1Level B: 1Level C: 1Level D: 2
Evidence Items
Showing CIViC evidence rows where gene = FIP1L1::PDGFRA and variant = Fusion.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Sensitivity/Response | Myeloid And Lymphoid Neoplasms With Eosinophilia And Abnormalities Of PDGFRA, PDGFRB, And FGFR1 | Imatinib | 4 |
| A | Predictive | Supports | Sensitivity/Response | Myeloid And Lymphoid Neoplasms With Eosinophilia And Abnormalities Of PDGFRA, PDGFRB, And FGFR1 | Imatinib | 3 |
| C | Predictive | Supports | Sensitivity/Response | Myeloid And Lymphoid Neoplasms With Eosinophilia And Abnormalities Of PDGFRA, PDGFRB, And FGFR1 | Imatinib | 3 |
| D | Predictive | Supports | Sensitivity/Response | Myeloid And Lymphoid Neoplasms With Eosinophilia And Abnormalities Of PDGFRA, PDGFRB, And FGFR1 | Ponatinib | 3 |
| D | Predictive | Supports | Sensitivity/Response | Acute Myeloid Leukemia | Sorafenib,Sunitinib | 3 |