Variant Summary
- Also known as
- ASP594ALA,RS121913338
- HGVS
- ENST00000288602.6:c.1781A>C,NC_000007.13:g.140453154T>G,NM_004333.4:c.1781A>C,NP_004324.2:p.Asp594Ala
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level E: 1
Evidence Items
Showing CIViC evidence rows where gene = BRAF and variant = D594A.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| E | Predictive | Supports | Sensitivity/Response | Skin Melanoma | Sorafenib,Mitogen-Activated Protein Kinase Kinase Inhibitor | 3 |