CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Overexpression

Overexpression

CIViC ID: 602 · Gene: CDK6

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
3

Evidence Level Distribution

Level B: 1Level D: 2

Evidence Items

Showing CIViC evidence rows where gene = CDK6 and variant = Overexpression.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsResistanceEstrogen-receptor Positive Breast CancerFulvestrant4
DPredictiveSupportsSensitivity/ResponseEstrogen-receptor Positive Breast CancerPalbociclib,Fulvestrant2
DPredictiveSupportsSensitivity/ResponseGlioblastoma Proneural SubtypePalbociclib2