Variant Summary
- Also known as
- ASP835HIS,RS121913488
- HGVS
- NM_004119.2:c.2503G>C,NP_004110.2:p.Asp835His,ENST00000241453.7:c.2503G>C,NC_000013.10:g.28592642C>G
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level C: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = FLT3 and variant = D835H.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Resistance | Acute Myeloid Leukemia | Sorafenib | 3 |
| D | Predictive | Supports | Sensitivity/Response | Acute Myeloid Leukemia | Gilteritinib | 2 |