Variant Summary
- Also known as
- Q503X,GLN503TER
- HGVS
- NC_000001.10:g.65321333G>A,ENST00000342505.4:c.1507C>T
- Variant Type(s)
- stop_gained
- Evidence Items
- 1
Evidence Level Distribution
Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = JAK1 and variant = Q503*.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Resistance | Skin Melanoma | Pembrolizumab | 4 |