CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

R140

CIViC ID: 62 · Gene: IDH2

Variant Summary

Also known as
ARG140
HGVS
Variant Type(s)
protein_altering_variant
Evidence Items
5

Evidence Level Distribution

Level B: 5

Evidence Items

Showing CIViC evidence rows where gene = IDH2 and variant = R140.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticDoes Not SupportMyelodysplastic Syndrome3
BPrognosticSupportsBetter OutcomeAcute Myeloid Leukemia3
BPrognosticDoes Not SupportAcute Myeloid Leukemia2
BPrognosticDoes Not SupportAcute Myeloid Leukemia2
BPrognosticDoes Not SupportMyelodysplastic Syndrome2