CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 645 · Gene: IDH1

Variant Summary

HGVS
—
Variant Type(s)
transcript_variant
Evidence Items
6

Evidence Level Distribution

Level A: 1Level B: 3Level C: 1Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = IDH1 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticSupportsBetter OutcomeChondrosarcoma4
BPrognosticSupportsBetter OutcomeBrain Glioma3
DPredictiveSupportsSensitivity/ResponseBrain GliomaOlaparib3
APredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaIvosidenib3
BPredictiveSupportsSensitivity/ResponseCholangiocarcinomaIvosidenib3
CPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaVenetoclax3