Variant Summary
- Also known as
- SER463PRO,RS1057519714
- HGVS
- NC_000006.11:g.152415537T>C,ENST00000440973.1:c.1387T>C,NM_000125.3:c.1387T>C,NP_000116.2:p.Ser463Pro
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = ESR1 and variant = S463P.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Resistance | Estrogen-receptor Positive Breast Cancer | Aromatase Inhibitor | 2 |