Variant Summary
- HGVS
- —
- Variant Type(s)
- gene_variant
- Evidence Items
- 3
Evidence Level Distribution
Level B: 3
Evidence Items
Showing CIViC evidence rows where gene = STK11 and variant = Mutation.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predisposing | Supports | Predisposition | Peutz-Jeghers Syndrome | 4 | |
| B | Predictive | Supports | Resistance | Lung Adenocarcinoma | Nivolumab,Pembrolizumab,Atezolizumab | 4 |
| B | Predictive | Does Not Support | Sensitivity/Response | Lung Non-small Cell Carcinoma | Vistusertib | 2 |