CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Loss-of-function

Loss-of-function

CIViC ID: 721 · Gene: CYP2D6

Variant Summary

HGVS
—
Variant Type(s)
loss_of_function_variant
Evidence Items
1

Evidence Level Distribution

Level B: 1

Evidence Items

Showing CIViC evidence rows where gene = CYP2D6 and variant = Loss-of-function.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticDoes Not SupportPoor OutcomeBreast Cancer4