Variant Summary
- Also known as
- R226X,ARG226TER,R128*,RS63751615
- HGVS
- NM_000249.3:c.676C>T,NP_000240.1:p.Arg226Ter,ENST00000231790.2:c.676C>T,NC_000003.11:g.37053589C>T
- Variant Type(s)
- stop_gained
- Evidence Items
- 1
Evidence Level Distribution
Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = MLH1 and variant = R226*.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Oncogenic | Supports | Oncogenicity | Colorectal Cancer | 1 |