CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

G12

CIViC ID: 76 · Gene: KRAS

Variant Summary

Also known as
GLY12
HGVS
Variant Type(s)
protein_altering_variant
Evidence Items
7

Evidence Level Distribution

Level B: 7

Evidence Items

Showing CIViC evidence rows where gene = KRAS and variant = G12.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticDoes Not SupportBetter OutcomeColorectal Cancer4
BPrognosticSupportsPoor OutcomeMultiple Myeloma4
BDiagnosticDoes Not SupportPositiveLung Non-small Cell Carcinoma3
BPrognosticDoes Not SupportLung Non-small Cell Carcinoma3
BPrognosticSupportsPoor OutcomeMultiple Myeloma3
BPrognosticSupportsPoor OutcomeLung Non-small Cell Carcinoma3
BDiagnosticSupportsPositiveAcute Leukemia3