CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 797 · Gene: POLE

Variant Summary

HGVS
—
Variant Type(s)
gene_variant
Evidence Items
2

Evidence Level Distribution

Level C: 2

Evidence Items

Showing CIViC evidence rows where gene = POLE and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredictiveSupportsSensitivity/ResponseGlioblastomaPembrolizumab3
CPredictiveSupportsSensitivity/ResponseEndometrial CancerPembrolizumab3