Variant Summary
- HGVS
- —
- Variant Type(s)
- loss_of_function_variant
- Evidence Items
- 1
Evidence Level Distribution
Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = MSH2 and variant = Loss.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Sensitivity/Response | Transitional Cell Carcinoma | Anti-PD-1 Monoclonal Antibody MEDI0680,Durvalumab | 3 |