CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Loss-of-function

Loss-of-function

CIViC ID: 819 · Gene: PTPRB

Variant Summary

HGVS
—
Variant Type(s)
loss_of_function_variant
Evidence Items
2

Evidence Level Distribution

Level B: 1Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = PTPRB and variant = Loss-of-function.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BDiagnosticSupportsPositiveAngiosarcoma3
DPredictiveSupportsSensitivity/ResponseAngiosarcomaVatalanib,Sunitinib3