Variant Summary
- HGVS
- —
- Variant Type(s)
- —
- Evidence Items
- 6
Evidence Level Distribution
Level A: 1Level B: 4Level E: 1
Evidence Items
Showing CIViC evidence rows where gene = MGMT and variant = Promoter Methylation.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| A | Predictive | Supports | Sensitivity/Response | Glioblastoma | Temozolomide | 5 |
| B | Prognostic | Supports | Better Outcome | Glioblastoma | 5 | |
| B | Prognostic | Supports | Better Outcome | Glioblastoma | 4 | |
| B | Predictive | Supports | Sensitivity/Response | Glioblastoma | Carmustine | 4 |
| E | Predictive | Supports | Sensitivity/Response | Glioblastoma | O6-Benzylguanine | 4 |
| B | Prognostic | Supports | Better Outcome | Oligodendroglioma | 4 |