Variant Summary
- Also known as
- HIS845TYR,RS1057519814
- HGVS
- NM_006206.4:c.2533C>T,NP_006197.1:p.His845Tyr,NC_000004.11:g.55152101C>T,ENST00000257290.5:c.2533C>T
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = PDGFRA and variant = H845Y.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Melanoma | Imatinib,Crenolanib | 3 |