Variant Summary
- Also known as
- RS121913237,GLY12ASP
- HGVS
- NM_002524.4:c.35G>A,NP_002515.1:p.Gly12Asp,NC_000001.10:g.115258747C>T,ENST00000369535.4:c.35G>A
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level B: 1Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = NRAS and variant = G12D.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Resistance | Colorectal Cancer | Cetuximab,Irinotecan | 3 |
| B | Predictive | Supports | Resistance | Colorectal Cancer | Cetuximab | 0 |