Variant Summary
- Also known as
- RS104886003,GLU545GLN
- HGVS
- NM_006218.3:c.1633G>C,NP_006209.2:p.Glu545Gln,NC_000003.11:g.178936091G>C,ENST00000263967.3:c.1633G>C
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = PIK3CA and variant = E545Q.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Does Not Support | Resistance | Colorectal Cancer | Cetuximab,Irinotecan | 3 |