CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/E545G

E545G

CIViC ID: 883 · Gene: PIK3CA

Variant Summary

Also known as
RS121913274,GLU545GLY
HGVS
NM_006218.3:c.1634A>G,NP_006209.2:p.Glu545Gly,NC_000003.11:g.178936092A>G,ENST00000263967.3:c.1634A>G
Variant Type(s)
missense_variant
Evidence Items
1

Evidence Level Distribution

Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = PIK3CA and variant = E545G.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsResistanceMelanomaVemurafenib2