Variant Summary
- Also known as
- RS17851045,GLN61HIS
- HGVS
- NM_004985.4:c.183A>C,NP_004976.2:p.Gln61His,NC_000012.11:g.25380275T>G,ENST00000256078.4:c.183A>C
- Variant Type(s)
- missense_variant
- Evidence Items
- 3
Evidence Level Distribution
Level C: 2Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = KRAS and variant = Q61H.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Resistance | Colorectal Cancer | Cetuximab,Chemotherapy | 3 |
| D | Oncogenic | Supports | Oncogenicity | Cancer | 3 | |
| C | Predictive | Supports | Resistance | Colorectal Cancer | Cetuximab | 0 |