CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Q61

Q61

CIViC ID: 94 · Gene: NRAS

Variant Summary

Also known as
GLN61
HGVS
—
Variant Type(s)
missense_variant
Evidence Items
8

Evidence Level Distribution

Level B: 7Level C: 1

Evidence Items

Showing CIViC evidence rows where gene = NRAS and variant = Q61.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsResistanceMelanomaVemurafenib4
BDiagnosticSupportsPositiveMelanoma3
BPredictiveDoes Not SupportResistanceColorectal CancerCetuximab3
BPrognosticSupportsFollicular Thyroid Carcinoma3
BPredictiveSupportsSensitivity/ResponseSkin MelanomaBinimetinib2
CPredictiveSupportsSensitivity/ResponseSkin MelanomaSelumetinib2
BPredictiveSupportsResistanceColorectal CancerCetuximab,Chemotherapy2
BPrognosticDoes Not SupportPoor OutcomeFollicular Thyroid Carcinoma2