CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/V561D

V561D

CIViC ID: 941 · Gene: PDGFRA

Variant Summary

Also known as
RS121908586
HGVS
NM_006206.5:c.1682T>A,NP_006197.1:p.Val561Asp,NC_000004.11:g.55141036T>A,ENST00000257290.5:c.1682T>A
Variant Type(s)
missense_variant
Evidence Items
4

Evidence Level Distribution

Level C: 1Level D: 3

Evidence Items

Showing CIViC evidence rows where gene = PDGFRA and variant = V561D.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveDoes Not SupportResistanceCancerImatinib2
DPredictiveDoes Not SupportResistanceCancerSunitinib2
DPredictiveDoes Not SupportResistanceCancerImatinib Mesylate2
CPredictiveSupportsSensitivity/ResponseGastrointestinal Stromal TumorImatinib1