Variant Summary
- Also known as
- GLN61LEU,RS11554290
- HGVS
- NP_002515.1:p.Gln61Leu,NC_000001.10:g.115256529T>A,NM_002524.4:c.182A>T,ENST00000369535.4:c.182A>T
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level C: 2
Evidence Items
Showing CIViC evidence rows where gene = NRAS and variant = Q61L.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Resistance | Colorectal Cancer | Irinotecan,Cetuximab | 3 |
| C | Predictive | Supports | Sensitivity/Response | Melanoma | Temozolomide | 2 |