CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/W557_K558del

W557_K558del

CIViC ID: 961 · Gene: KIT

Variant Summary

HGVS
—
Variant Type(s)
conservative_inframe_deletion
Evidence Items
4

Evidence Level Distribution

Level C: 1Level D: 3

Evidence Items

Showing CIViC evidence rows where gene = KIT and variant = W557_K558del.

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredictiveSupportsResistanceGastrointestinal Stromal TumorSunitinib3
DPredictiveSupportsSensitivity/ResponseGastrointestinal Stromal TumorPonatinib,Imatinib3
DPredictiveDoes Not SupportResistanceCancerImatinib2
DPredictiveSupportsSensitivity/ResponseGastrointestinal Stromal TumorRegorafenib Anhydrous,Sunitinib2